The purpose of this notice is to solicit proposals for a single cooperative agreement between NOAA and an institution of higher learning as authorized in the Ocean and Coastal Mapping Integration Act and the Hydrographic Services Improvement Act. Proposals submitted in response to this announcement should advance the purposes of the Acts by addressing the Program Priorities described in this announcement.A key objective of this opportunity is to advance the nation’s capacity for modern ocean and coastal mapping through the development, integration, and operational transition of innovative technologies and workflows. This program prioritizes the expansion of hydrographic and cartographic data accessibility, interoperability, and usability, while enhancing efficiency across acquisition, p...

This notice announces the opportunity to apply for funding under the Rural Health Clinic Technical Assistance Program. The Rural Health Clinic Technical Assistance (RHC TA) Program funds an entity to provide technical assistance (TA) to Rural Health Clinics (RHCs) through targeted support, specialized expertise, and guidance. The purpose of this program is to:Identify key policy, regulatory, programmatic, and clinical issues facing RHCs.Inform RHCs and other rural stakeholders about key RHC issues that affect, or could affect, health care delivery and improve care. Identify and disseminate information on tools, resources, and strategies as possible solutions to challenges faced by RHCs.

This Notice of Funding Opportunity (NOFO) supports critical minerals and materials. Critical minerals and materials (CMM) are the building blocks for technologies foundational to U.S. energy dominance, national security, and industrial competitiveness. To build a secure domestic supply of CMMs, the U.S. Department of Energy (DOE) aims to support collaborative industry partnerships to prototype and pilot innovative processing technologies that are currently only proven at the bench scale to address CMM challenges in high impact areas. The CMM Accelerator program will advance these mid-stage innovations through validation, benchmarking, access to national lab test beds, testing in industry relevant environments, technoeconomic analysis, and life-cycle assessment. The program establishes a...

THIS IS NOT A REQUEST FOR APPLICATIONS. This announcement is to provide notice of NIC's continuation of Cooperative Agreement award 25JD03GLV4

Summary: The fiscal year 2026 (FY26) Pancreatic Cancer Research Program (PCARP) Translational Research Partnership Award supports partnerships between clinicians, population scientists, applied scientists and/or basic scientists that will accelerate the movement of promising ideas in pancreatic cancer toward clinical applications. The partnership must include at least one member with expertise in pancreatic cancer research or pancreatic cancer patient care. All applications must address at least one of the FY26 PCARP Focus Areas. ·        This award mechanism requires preliminary data to support feasibility of the research hypothesis(es) and research approaches. However, these data do not necessarily need to originate from studies of pancreatic ca...

This NOFO has been amended. Please see the amended Notice of Funding Opportunity for additional information.As 2027 marks 15 years since the loss of Ambassador J. Christopher Stevens, and in honor of his enduring legacy, the Global Leaders Division, Office of Citizen Exchanges, Bureau of Educational and Cultural Affairs (ECA), invites proposal submissions for two cooperative agreements to design, administer, and implement activities under the broader J. Christopher Stevens Virtual Exchange Initiative (JCSVEI).ECA anticipates making two separate cooperative agreements to design, implement, and manage the FY 2026 J. Christopher Stevens Virtual Exchange Initiative (JCSVEI) under two distinct program options: (1) J. Christopher Stevens Virtual Exchange Initiative and (2) J. Christopher Stev...

The Applied Mathematics program supports mathematics research motivated by and contributing to the solution of problems arising in science and engineering. Successful proposals must demonstrate mathematical innovation, as well as breadth and quality of impact on applications. Projects that additionally provide opportunities for rigorous mathematical training of junior applied mathematicians through their involvement in research are encouraged. The proposals considered by the Applied Mathematics program may range from single investigator to interdisciplinary team projects. Conferences Proposals to the Applied Mathematics program for conferences or workshops should be submitted through the program solicitation "Conferences and Workshops in the Mathematical Sciences" (link below). Principa...

Summary: The fiscal year 2026 (FY26) Traumatic Brain Injury and Psychological Health Research Program (TBIPHRP) Clinical Trial Award (CTA) intends to support clinical trials with the potential to have a significant impact on psychological health conditions and/or traumatic brain injury (TBI) through clinical applications, including health care products, technologies and/or practice guidelines.  Distinctive Features: Funding from this award mechanism must support a clinical trial.·        Clinical trials may be designed to evaluate a wide range of interventions, including new drugs, biologics, medical devices, diagnostics, therapies and behavioral health strategies.·        Preliminary data are required....

This Notice of Funding Opportunity (NOFO) encourages applications for support of resources that will provide access to state-of-the-art equipment, technologies, research tools, materials, organisms, software, and/or services to a substantial regional (multi-state) or national user base. Only those resources with technical capabilities that fall within the NIGMS-supported program areas are eligible for awards. The resources should already be established or may be formed through consolidation of existing local or regional facilities. The intent is to provide resource access to investigators without regard to the specific biomedical focus of their research, while not duplicating or replacing resources supported by sources such as other NIH Institutes and Centers (ICs) or host institutions....

This Research Announcement represents a solicitation for a research thrust, entitled Protean, that will focus on identifying novel ways to restore protein function to targets of chemical threat agents.

The AFG Program provides financial assistance directly to eligible fire departments, nonaffiliated emergency medical service (EMS) organizations, and State Fire Training Academies (SFTAs) to equip and train emergency personnel to recognized standards, outfit responders with compliant personal protective equipment, provide funding to retrofit or modify facilities to protect personnel from known health hazards, acquire emergency response vehicles, design and implement health, wellness and resiliency programs that prepare responders for incident response, enhance operational efficiencies, foster interoperability, and support community resilience. 

NIMH seeks applications for pilot research to adapt, optimize, and test behavioral interventions that address common sleep problems in adolescents and young adults with or at risk for a mental health disorder. This notice of funding opportunity (NOFO) supports pilot clinical trials designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach in real world settings. Applications should aim to conduct a preliminary test of the intervention's impact on sleep and mental health outcomes, as well as an examination of the mechanisms that underlie the intervention's effectiveness, and to obtain preliminary data needed as a prerequisite for larger-scale effectiveness trials. In addition, interdisciplinary, collaborative teams of investiga...

The Groundwater and Streamflow Information Program of the USGS is offering a cooperative agreement funding opportunity to States, federally recognized Native American Tribal governments, or local water-resources agencies that collect groundwater data to participate in the National Ground-Water Monitoring Network. The USGS is working to develop and administer the National Ground-Water Monitoring Network (NGWMN). This funding opportunity is to support data providers for the National Ground-Water Monitoring Network.Legal authority for this opportunity is provided under Public Law 111-11, Subtitle F—Secure Water: Section 9507 "Water Data Enhancement by the United States Geological Survey," as amended in 2024 by Public Law 118-174. Funds will be used to support connecting new data providers ...

The DOE Office of Science (SC), Office of Critical Minerals and Energy Innovation (CMEI), Office of Environmental Management (EM), Office of Nuclear Energy (NE), Office of Electricity (OE), and Hydrocarbons and Geothermal Office (HGEO) hereby announce interest in receiving applications from interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks. By achieving AI advantage, these teams will advance the DOE's mission and ensure America’s security and prosperity by addressing energy, environmental, and nuclear challenges through science and technology. Teams are encouraged to leverage the exten...

This is a notice of funding opportunity (NOFO) for the BJA FY2025 Justice Information Sharing Training and Technical Assistance Program (RISS Support). This funding opportunity seeks to continue to provide support services to the six Regional Information Sharing Systems (RISS) Centers and the RISS Technology Support Center (RTSC) under BJA’s Justice Information Sharing Training and Technical Assistance (JISTTA) Program. This is a carve out from the RISS allocation.

The Collaboratory to Advance Mathematics Education and Learning (CAMEL) for K-12 initiative aims to advance mathematics learning and education through purposeful collaboration that draws on the interdisciplinary Science of Learning (including neuroscience; cognitive, developmental, and social sciences; computer science; machine learning; engineering; and education research), deep experiences in education practice and teaching, and innovations in the use of data science, AI and technology. Through an agreement with philanthropic partners, including the Walton Family Foundation (WFF), CAMEL consists of two phases. Phase I invites proposals for the creation of new research networks to support the generation of high value datasets that aim to advance math learning and education. These resea...

Malaysia-wide outreach with physical advising centers in the Klang Valley, Penang, and East Malaysia. The Public Diplomacy Section at the United States Embassy in Malaysia announces an open competition for organizations to submit applications to promote U.S. higher education opportunities for Malaysian students at the graduate and undergraduate levels. This project includes maintaining physical presences of at least three EducationUSA advising centers manned by trained EducationUSA advisors that will serve as the primary resource for accurate, comprehensive, and current information about studying in the United States. Programmatic requirements will include education fairs, presentations at secondary schools and universities, and other programs in cooperation with the U.S. Embassy. Freed...

Summary: The fiscal year 2026 (FY26) Autism Research Program (ARP) Clinical Trial Award supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of autism. Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance and/or emerging approaches and technologies. Proposed projects may range from small proof-of-concept trials (e.g., pilot, first-in-human, phase 0) to demonstrate the feasibility or inform the design of more advanced trials through large-scale trials to determine efficacy in relevant patient populations.Distinctive Features: Applications are strongly encouraged to address one of the FY26 ARP Clinical Trial Award Areas of Inte...

The Administration for Children and Families at the U.S. Department of Health and Human Services (HHS) is soliciting applications in support of the administration of the School Safety Enhancement (SSE) program on behalf of the U.S. Department of Education (ED) and the Secretary of Education (the Secretary). The SSE program provides competitive grants to State educational agencies (SEAs) to develop, implement, and strengthen statewide school safety systems and the physical security of schools.Estimated Range of Awards: $500,000 - 5,000,000 per 36-month project period. Estimated Number of Awards: 30. Project Period: Up to 36 months. 

This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. The purpose of this NOFO is to seek applications in a limited competition for the Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Centers (IDDRCs). This NOFO invites applications to undergo peer review for research center grants designed to advance the diagnosis, prevention, treatment, and amelioration of intellectual and developmental disabilities (IDD) and is limited to IDDRCs funded under RFA-HD-20-016 or RFA-HD-21-009. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) ...

Summary: The fiscal year 2026 (FY26) Epilepsy Research Program (ERP) seeks to advance post-traumatic epilepsy (PTE) research through development of investigators new to the PTE field. To accomplish this, the ERP is soliciting Faculty members to join the Virtual Post-Traumatic Epilepsy Research Center (ViP-TERC). The ERP ViP-TERC is a unique, interactive virtual research center providing intensive mentoring, national networking, collaborations, and a peer group for new PTE investigators. The overarching goal of the ViP-TERC is to develop successful, highly productive PTE researchers in a collaborative research and career development environment to enhance quality and expand quantity of the PTE research field.Distinctive Features: This award mechanism focuses on both the Faculty member’s ...

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) encourages Exploratory/Developmental Phased Innovation (R61/R33) grant applications to support development of clinical trials to treat critical and co-occurring health conditions in individuals with Down syndrome. The proposed research aims should be milestone-driven. The total project period for an application submitted in response to this NOFO may not exceed five years. This NOFO provides support for up to two years (R61 phase) for preliminary/developmental/planning studies, followed by possible transition to clinical trial support (R33)...

This notice of funding opportunity (NOFO) invites applications designed to examine the efficacy and clinical effectiveness of multimodality digital health technology approaches to the remote management of diabetes.

The U.S. Department of State Bureau of Counterterrorism (CT) announces a funding opportunity to establish a Western Hemisphere Counterterrorism Legal and Financial Disruption Program. The program will strengthen recipients’ ability to hold Foreign Terrorist Organizations (FTOs) accountable by improving legal frameworks and disrupting their financial networks. This initiative supports the 2025 National Security Strategy and the Department’s Agency Strategic Plan by deepening regional partnerships to enhance security, counter transnational threats, and protect U.S. interests in the Western Hemisphere. The program will deliver structured legal and financial-disruption training for investigators, prosecutors, and judges across Latin America and the Caribbean. It will focus on investigating,...

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for research on developing a comprehensive and cohesive understanding of cancer metastasis. Towards this goal, the NCI will support U54 Specialized Centers that together will continue to serve as the hub of the Metastasis Research Network (MetNet). Each MetNet Center should propose an overarching scientific theme that will be pursued through two or three scientific inter- and multidisciplinary basic research projects. The projects should use integrative system level approaches to elucidate and integrate a mechanistic understanding of the non-linear, dynamic, and emergent processes in metastasis. Overarching themes should encompass the interplay between at least two central elemen...